Sister Cohesion and Structural Axis Components Mediate Homolog Bias of Meiotic Recombination
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چکیده
منابع مشابه
Sister Cohesion and Structural Axis Components Mediate Homolog Bias of Meiotic Recombination
Meiotic double-strand break (DSB)-initiated recombination must occur between homologous maternal and paternal chromosomes ("homolog bias"), even though sister chromatids are present. Through physical recombination analyses, we show that sister cohesion, normally mediated by meiotic cohesin Rec8, promotes "sister bias"; that meiosis-specific axis components Red1/Mek1kinase counteract this effect...
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ژورنال
عنوان ژورنال: Cell
سال: 2010
ISSN: 0092-8674
DOI: 10.1016/j.cell.2010.11.015